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71845-66-4

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71845-66-4 Structure

71845-66-4 Structure
IdentificationBack Directory
[Name]

Prostaglandin E2 isopropyl ester
[CAS]

71845-66-4
[Synonyms]

NOHLKSJQMSPOTB-FZNVCOGTSA-N
Prostaglandin E2 isopropyl ester
Prostaglandin E2 isopropyl ester Exclusive
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-9-oxo-, 1-methylethyl ester, (5Z,11α,13E,15S)- (9CI)
[Molecular Formula]

C23H38O5
[MDL Number]

MFCD18427992
[MOL File]

71845-66-4.mol
[Molecular Weight]

394.54
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 30 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): <50 μg/ml
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)Health Hazard (GHS08)
GHS02,GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H360-H336
[Precautionary statements ]

P201-P202-P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

Prostaglandin E2 (PGE2) isopropyl ester is a more lipophilic form of the free acid, PGE2. PG esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid by endogenous esterases upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of PGs show greatly diminished receptor activity in vitro compared to the parent free acids.
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