| Identification | More | [Name]
1-Methyl-L-histidine | [CAS]
332-80-9 | [Synonyms]
1-METHYLHISTIDINE
1-METHYL-L-HISTIDINE
3-(1-METHYLIMIDAZOL-4-YL)-L-ALANINE
3-(1-METHYLIMIDAZOL-5-YL)-L-ALANINE
3-METHYL-L-HISTIDINE
H-HIS(1-ME)-OH
H-HIS(3-ME)-OH
H-HIS(PI-ME)-OH
H-HIS(TAU-ME)-OH
HISTIDINE(3-ME)-OH
H-N-P-METHYL-L-HISTIDINE
L-1-METHYLHISTIDINE
L-3-METHYLHISTIDINE
METHYLHISTIDINE, L-1-
METHYLHISTIDINE, L-3-
NH-METHYL-HIS-OH
N-(IMIDAZOLE-1-METHYL)-L-HISTIDINE
N-PI-METHYL-L-HISTIDINE
N-TAU-METHYL-L-HISTIDINE
PI-METHYL-L-HISTIDINE | [EINECS(EC#)]
206-368-0 | [Molecular Formula]
C7H11N3O2 | [MDL Number]
MFCD00005295 | [Molecular Weight]
169.18 | [MOL File]
332-80-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
~240 °C (dec.) (lit.) | [alpha ]
-24 º (c=2% in H2O) | [Boiling point ]
298.47°C (rough estimate) | [density ]
1.2509 (rough estimate) | [refractive index ]
1.5950 (estimate) | [storage temp. ]
2-8°C(protect from light) | [solubility ]
Methanol (Slightly), Water (Slightly, Sonicated) | [form ]
Solid | [pka]
1.69(at 25℃) | [color ]
Off-White to Pale Beige | [optical activity]
[α]20/D 24±1°, c = 2% in H2O | [BRN ]
9727 | [Stability:]
Hygroscopic | [CAS DataBase Reference]
332-80-9(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes .
S22:Do not breathe dust . | [WGK Germany ]
3
| [HS Code ]
29332900 |
| Hazard Information | Back Directory | [Chemical Properties]
Beige powder | [Uses]
The urinary 1- and 3-methylhistidine (1- and 3-MH) metabolites as potential biomarkers of skeletal muscle toxicity. These metabolites were highly correlated to sex-, dose-, and time-dependent developm
ent of cerivastatin-induced myotoxicity.
Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown. | [Uses]
The urinary 1- and 3-methylhistidine (1- and 3-MH) metabolites as potential biomarkers of skeletal muscle toxicity. These metabolites were highly correlated to sex-, dose-, and time-dependent development of cerivastatin-induced myotoxicity. Natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown. | [Definition]
ChEBI: N(tele)-methyl-L-histidine is a L-histidine derivative in which the methyl group is at N(tele)-position. It has a role as a human metabolite. It is a L-histidine derivative and a non-proteinogenic L-alpha-amino acid. It is a tautomer of a N(tele)-methyl-L-histidine zwitterion. | [reaction suitability]
reaction type: solution phase peptide synthesis |
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