| Identification | Back Directory | [Name]
4,4'-Di-O-methylellagic acid | [CAS]
3374-77-4 | [Synonyms]
Nasutin C
4'-Di-O-methylellagic acid
4,4'-Di-O-methylellagic acid
Ellagic acid 4,4'-dimethyl ether
[1]Benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, 3,8-dihydroxy-2,7-dimethoxy- | [Molecular Formula]
C16H10O8 | [MOL File]
3374-77-4.mol | [Molecular Weight]
330.25 |
| Hazard Information | Back Directory | [Description]
4,4'-di-O-methylellagic acid is the most effective compound in the inhibition of colon cancer cell proliferation. | [Uses]
4,4'-Di-O-methylellagic acid (4,4'-DiOMEA; Nasutin C) can be isolated from the Australian termites. 4,4'-Di-O-methylellagic acid is blue-fluorescent under ultra-violet light[1]. 4,4'-Di-O-methylellagic acid inhibits colon cancer cell proliferation via the wnt signal pathway[2]. | [target]
Wnt/β-catenin | [References]
[1] B. P. MOORE, et al. Coumarin-like Substances from Australian Termites. Nature. 1962.
[2] Ana Ramírez de Molina, et al. The ellagic acid derivative 4,4'-di-O-methylellagic acid efficiently inhibits colon cancer cell growth through a mechanism involving WNT16. J Pharmacol Exp Ther. 2015, 353, 2. DOI:10.1124/jpet.114.221796 |
|
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
|