| Identification | Back Directory | [Name]
(D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDE | [CAS]
340821-13-8 | [Synonyms]
(D-Phe5,Cys6
H-D-PHE-CYS-PHE-N-ME-D-TRP-LYS-THR-CYS-THR-NH2
(D-Phe,Cys·11,N-Me-D-Trp)-Somatostatin-14 (5-12) amide
(D-PHE5,CYS6,11,N-ME-D-TRP8)-SOMATOSTATIN-14 (5-12) AMIDE
H-D-Phe-Cys-Phe-N-Me-D-Trp-Lys-Thr-Cys-Thr-NH2 , (Disulfide bond)
(N-Me-D-Trp4,Thr8)-Octreotide aMide, (N-Me-D-Trp4)-Octreotate aMide
L-Threoninamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-N-methyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide | [Molecular Formula]
C50H67N11O10S2 | [MDL Number]
MFCD05663467 | [MOL File]
340821-13-8.mol | [Molecular Weight]
1046.26 |
| Hazard Information | Back Directory | [Uses]
(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide (Compound 4) is a somatostatin analog with Kds of 0.61, 11.05, 23.5, 1200 and >1000 nM for SSTR5, SSTR3, SSTR2, SSTR1 and SSTR4, respectively[1]. | [References]
[1] Nikiforovich GV, et al. Molecular modeling suggests conformational scaffolds specifically targeting five subtypes of somatostatin receptors. Chem Biol Drug Des. 2007 Mar;69(3):163-9. DOI:10.1111/j.1747-0285.2007.00493.x |
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