| Identification | Back Directory | [Name]
(D-TRP8,D-CYS14)-SOMATOSTATIN-14 | [CAS]
61950-59-2 | [Synonyms]
[DTRP8,DCYS14] SRIF
trp(8)-cys(14)-somatostati
[D-TRP8,D-CYS14]-SOMATOSTATIN
somatostatin, Trp(8)-Cys(14)-
somatostatin [D-Trp8,D-Cys14]
(D-TRP8,D-CYS14)-SOMATOSTATIN-14
Somatostatin (sheep), 8-D-tryptophan-14-D-cysteine- (9CI)
ALA-GLY-CYS-LYS-ASN-PHE-PHE-D-TRP-LYS-THR-PHE-THR-SER-D-CYS
H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-D-TRP-LYS-THR-PHE-THR-SER-D-CYS-OH
H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-D-Trp-Lys-Thr-Phe-Thr-Ser-D-Cys-OH, (Disulfide bond)
ALA-GLY-CYS-LYS-ASN-PHE-PHE-D-TRP-LYS-THR-PHE-THR-SER-D-CYS (DISULFIDE BRIDGE:CYS3-CYS14) | [Molecular Formula]
C76H104N18O19S2 | [MDL Number]
MFCD00076764 | [MOL File]
61950-59-2.mol | [Molecular Weight]
1637.88 |
| Hazard Information | Back Directory | [Uses]
(D-Trp8,D-Cys14)-Somatostatin-14 is a Somatostatin synthetic analogue. (D-Trp8,D-Cys14)-Somatostatin-14 can be used for the research of metabolic related diseases[1][2]. | [in vivo]
(D-Trp8,D-Cys14)-Somatostatin-14 (12 μg/100g; i.p.) not modify intestinal absorption in vivo of carbohydrates in hamster intestine, but inhibits brush-border lactase activity in females[2]. | [References]
[1] Vécsei L, et, al. Somatostatin and (D-Trp8, D-Cys14)-somatostatin delay extinction and reverse electroconvulsive shock induced amnesia in rats. Psychoneuroendocrinology. 1986;11(1):111-5. DOI:10.1016/0306-4530(86)90037-5
[2] Martínez-Sapi?a J, et, al. Somatostatin and its analogue (D-Trp8,D-Cys14)-somatostatin do not modify intestinal absorption in vivo of carbohydrates in hamster intestine, but they do modify some disaccharidases. Q J Exp Physiol. 1989 Nov;74(6):851-6. DOI:10.1113/expphysiol.1989.sp003355 |
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