| Identification | Back Directory | [Name]
Amino-PEG5-alcohol | [CAS]
34188-11-9 | [Synonyms]
NH2-PEG5-OH
Amino-PEG5-alcohol
14-amino-3,6,9,12-tetraoxatetradecanol
14-amino-3,6,9,12-tetraoxatetradecan-1-ol
3,6,9,12-Tetraoxatetradecan-1-ol, 14-amino- | [Molecular Formula]
C10H23NO5 | [MDL Number]
MFCD28950782 | [MOL File]
34188-11-9.mol | [Molecular Weight]
237.29 |
| Chemical Properties | Back Directory | [Boiling point ]
346.3±32.0 °C(Predicted) | [density ]
1.077±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DMF, DCM | [form ]
Liquid | [pka]
14.36±0.10(Predicted) | [color ]
Colorless to light yellow | [InChI]
InChI=1S/C10H23NO5/c11-1-3-13-5-7-15-9-10-16-8-6-14-4-2-12/h12H,1-11H2 | [InChIKey]
DEOUHEFHTMMUCM-UHFFFAOYSA-N | [SMILES]
C(O)COCCOCCOCCOCCN |
| Hazard Information | Back Directory | [Description]
Amino-PEG5-alcohol is an aqueousr soluble PEG linker with one amine and one hydroxyl group. The amine group is reactive with carboxylic acids, activated NHS esters etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. | [IC 50]
PEGs; Non-cleavable Linker | [References]
[1] Nathanael Gray, et al. Bifunctional molecules for degradation of egfr and methods of use. WO2017185036A1.
[2] Nianhe Han, et al. Derivatives of dolastatin 10 and uses thereof. WO2016192527A1. |
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