| Identification | Back Directory | [Name]
3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one | [CAS]
345222-92-6 | [Synonyms]
3-[(Aminosulfonyl)oxy]-7,8,9,10,11,12,13,14-octahydro-6H-benzo[b]cyclodeca[d]pyran-6-one | [Molecular Formula]
C17H21NO5S | [MOL File]
345222-92-6.mol | [Molecular Weight]
351.42 |
| Chemical Properties | Back Directory | [Melting point ]
183-185 °C(Solvent: Tetrahydrofuran ; Hexane) | [Boiling point ]
567.4±60.0 °C(Predicted) | [density ]
1.36±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [pka]
8.27±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Steroid sulfatase-IN-8 (7) is a STS inhibitor with PM IC50 value of 1 nM, JEG-3 IC50 of 0.025 nM, respecively[1]. | [References]
[1] L W Lawrence Woo, et al. Structure-activity relationship for the first-in-class clinical steroid sulfatase inhibitor Irosustat (STX64, BN83495). ChemMedChem. 2011 Nov 4;6(11):2019-34. DOI:10.1002/cmdc.201100288 |
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