| Identification | More | [Name]
2-(2-BROMOPHENYL)-1,3-DIOXOLANE | [CAS]
34824-58-3 | [Synonyms]
1-BROMO-2-(1,3-DIOXOLAN-2-YL)BENZENE
2-(2-BROMOPHENYL)-1,3-DIOXOLANE
2-BROMOBENZALDEHYDE ETHYLENACETAL
2-BROMOBENZALDEHYDE ETHYLENE ACETAL
2-BROMO BENZALDEHYDE ETHYLENE GLYCOL ACETAL
RARECHEM AL BP 0014
1,3-Dioxolane, 2-(2-bromophenyl)-
2-BROMOBENZALDEHYDE ETHYLENE ACETAL, 98+% | [EINECS(EC#)]
628-917-7 | [Molecular Formula]
C9H9BrO2 | [MDL Number]
MFCD00155124 | [Molecular Weight]
229.07 | [MOL File]
34824-58-3.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless to pale yellow liquid | [Boiling point ]
126-127°C 5mm | [density ]
1.535 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.569(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
Liquid | [color ]
Clear colorless to pale yellow | [Water Solubility ]
Difficult to mix in water. | [BRN ]
1284374 | [CAS DataBase Reference]
34824-58-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
2
| [HS Code ]
29329900 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to pale yellow liquid | [Uses]
It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs. | [Synthesis]
The general procedure for the synthesis of 2-bromobenzaldehyde vinyl aldehyde from ethylene glycol and o-bromobenzaldehyde was as follows: to a solution of benzene (40 mL) containing 2-bromobenzaldehyde (5.30 mmol) was added ethylene glycol (1.26 mL, 22.6 mmol, 4.3 eq.) and p-toluenesulfonic acid (70 mg, 0.37 mmol, 0.07 eq.) in sequence. The reaction mixture was placed in a Dean-Stark apparatus and heated to reflux. After 4 hours of reaction, the reaction was cooled to room temperature and quenched with triethylamine, followed by concentration of the reaction solution under reduced pressure. Finally, purification by silica gel column chromatography afforded the target product 2-bromobenzaldehyde vinyl aldehyde in quantitative yield. | [References]
[1] Patent: US2004/147401, 2004, A1. Location in patent: Page 33
[2] Organic and Biomolecular Chemistry, 2009, vol. 7, # 6, p. 1106 - 1114
[3] Organic Letters, 2013, vol. 15, # 18, p. 4718 - 4721
[4] European Journal of Organic Chemistry, 2014, vol. 2014, # 10, p. 2084 - 2091
[5] Organic Process Research and Development, 2016, vol. 20, # 2, p. 253 - 261 |
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