| Identification | Back Directory | [Name]
1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one | [CAS]
350678-63-6 | [Synonyms]
WAY-300374
1-(3-(1H-imidazol-1-yl)propyl)-4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1H-pyrrol-2(5H)-one
2H-Pyrrol-2-one, 4-benzoyl-5-(4-fluorophenyl)-1,5-dihydro-3-hydroxy-1-[3-(1H-imidazol-1-yl)propyl]- | [Molecular Formula]
C23H20FN3O3 | [MDL Number]
MFCD01821506 | [MOL File]
350678-63-6.mol | [Molecular Weight]
405.42 |
| Chemical Properties | Back Directory | [Boiling point ]
665.1±55.0 °C(Predicted) | [density ]
1.30±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.50±1.00(Predicted) | [color ]
Off-white to light brown |
| Hazard Information | Back Directory | [Uses]
p53-MDM2-IN-4 (Example 4) is an inhibitor of p53-MDM2/X protein interaction, with a Ki value of 3.079 μM. p53-MDM2-IN-4 can be used in anti-tumor research[1]. | [References]
[1] Zhang W, et al. Pyrrylketone compound and application thereof as drug. CN102603717A. 2012-02-25. |
|
|