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351986-85-1

351986-85-1 Structure

351986-85-1 Structure
IdentificationBack Directory
[Name]

3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
[CAS]

351986-85-1
[Synonyms]

Vacuolin-1
Vacuolin-1 - CAS 351986-85-1 - Calbiochem
3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
(E)-4-(2-(3-iodobenzylidene)hydrazinyl)-6-Morpholino-N,N-diphenyl-1,3,5-triazin-2-aMine
Benzaldehyde, 3-iodo-, 2-[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone
4-[(2E)-2-(3-iodobenzylidene)hydrazinyl]-6-(morpholin-4-yl)-N,N-diphenyl-1,3,5-triazin-2-amine
[Molecular Formula]

C26H24IN7O
[MDL Number]

MFCD00321410
[MOL File]

351986-85-1.mol
[Molecular Weight]

577.42
Chemical PropertiesBack Directory
[Boiling point ]

719.7±70.0 °C(Predicted)
[density ]

1.53±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO:18.33(Max Conc. mg/mL);31.74(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:7):0.12(Max Conc. mg/mL);0.21(Max Conc. mM)
DMF:3.0(Max Conc. mg/mL);5.2(Max Conc. mM)
[form ]

White solid
[pka]

10.74±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
[Hazard Codes ]

Xn
[Risk Statements ]

22
Hazard InformationBack Directory
[Uses]

Vacuolin-1 is a cell-permeable triazine that inhibits Ca2+-dependent fusion of lysosomes to the cell membrane inhibiting release of lysosomal content.
[Biological Activity]

Cell permeable: yes''Primary Target
Ca2+-dependent fusion of lysosomes with the plasma membrane''Product does not compete with ATP.''Reversible: no
Spectrum DetailBack Directory
[Spectrum Detail]

3-Iodobenzaldehyde[4-(diphenylamino)-6-(4-morpholinyl)-1,3,5-triazin-2-yl]hydrazone(351986-85-1)1HNMR
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