| Identification | More | [Name]
4-Bromomethyl-7-methoxycoumarin | [CAS]
35231-44-8 | [Synonyms]
4-BROMOETHYL-7-METHOXYCOUMARIN
4-BROMOMETHYL-7-METHOXYCOUMARIN
BMC
BR-MMC
4-BROMOMETHYL-7-METHOXYCOUMARIN, FOR FLU ORESCENCE
4-Bromomethyl-7-methoxycoumain
4-BROMOMETHYL-7-METHOXYCOUMARIN (BR-MMC)
BR-MMC (=4-BROMOETHYL-7-METHOXYCOUMARIN)
4-BROMOMETHYL-7-METHOXYCOUMARIN [FOR HPLC LABELING]
Br-Mmc (=4-Bromomethyl-7-methoxycoumarin) [for HPLC Labeling]
BMC, Br-Mmc
2H-1-Benzopyran-2-one, 4-(bromomethyl)-7-methoxy-
4-(Bromomethyl)-7-methoxychromen-2-one
4-(Bromomethyl)-7-methoxy-2H-1-benzopyran-2-one
7-Methoxy-4-bromomethylcoumarin | [EINECS(EC#)]
252-448-3 | [Molecular Formula]
C11H9BrO3 | [MDL Number]
MFCD00006869 | [Molecular Weight]
269.09 | [MOL File]
35231-44-8.mol |
| Chemical Properties | Back Directory | [Appearance]
Light Green-Yellow Crystals | [Melting point ]
213-215 °C (lit.) | [Boiling point ]
385.3±42.0 °C(Predicted) | [density ]
1.552±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
chloroform: soluble20mg/mL, clear, colorless to faintly yellow | [form ]
Powder and/or Chunks | [color ]
Off-white to light yellow or beige | [Stability:]
Stable, but moisture and light-sensitive. Combustible. Incompatible with strong oxidizing agents. | [Water Solubility ]
insoluble | [Usage]
Used for derivatization, TLC and HPLC separation, and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B2 | [λmax]
330 nm (MeOH) | [BRN ]
187211 | [Biological Applications]
Analyzing/detecting
carboxylic acids;analyzing/labeling fatty acids;
detecting nitric oxide; detecting/separating bile
acids; labeling pyrimidine nucleobases;
anticancer agents; biomedical trace analysis;
herbicides; as a substrate for measuring
histone acetyltransferases (HATs) activity, peptidases
activity, sirtuin activity | [Major Application]
Detection of nitrated
explosives; measuring ultraviolet ray power;
photoacid generators; polyurethane foams;
photoresists silica nanoparticles | [InChI]
1S/C11H9BrO3/c1-14-8-2-3-9-7(6-12)4-11(13)15-10(9)5-8/h2-5H,6H2,1H3 | [InChIKey]
CTENSLORRMFPDH-UHFFFAOYSA-N | [SMILES]
COc1ccc2C(CBr)=CC(=O)Oc2c1 | [LogP]
2.730 (est) | [CAS DataBase Reference]
35231-44-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302-H315-H319-H335 | [Precautionary statements ]
P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
1759 | [WGK Germany ]
3
| [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29322090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Light Green-Yellow Crystals | [Uses]
4-Bromomethyl-7-methoxycoumarin has been used:
- as derivatization reagent in determination of 5-fluorouracil (5-FU) in human plasma by HPLC-tandem mass spectrometry
- as derivatization reagent in fluorescence detection of sodium monofluoroacetate (MFA-Na) in biological samples by HPLC
- in the synthesis of new caged derivatives of hydrolysis-resistant 8-bromoadenosine cyclic 3′,5′-monophosphate (8-Br-cAMP) and 8-bromoguanosine cyclic 3′,5′-monophosphate (8-Br-cGMP)
- in TLC and HPLC separation and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B2
| [Uses]
4-Bromomethyl-7-methoxycoumarin can be used as fluorescent label for fatty acids. For derivatization, TLC and HPLC separation, and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B2.
| [Uses]
Used for derivatization, TLC and HPLC separation, and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B2 | [Purification Methods]
The coumarin crystallises from boiling AcOH; the crystals are washed with AcOH, EtOH and dried in a vacuum; 1HNMR (TFA) 3.97s, 4.57s, 6.62s, 6.92-7.19m and 7.80d. [Secrist et al. Biochem Biophys Res Commun 45 1262 1971, Dünges Anal Chem 49 442 1977, Beilstein 18 III/IV 348.] |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|