| Identification | More | [Name]
5-CHLORO-2-FLUOROPHENYLBORONIC ACID | [CAS]
352535-83-2 | [Synonyms]
5-CHLORO-2-FLUOROBENZENEBORONIC ACID
5-CHLORO-2-FLUOROPHENYLBORONIC ACID
AKOS BRN-0727
5-Chloro-2-fluorobenzeneboronic acid 97%
5-Chloro-2-fluorobenzeneboronicacid97% | [EINECS(EC#)]
675-613-5 | [Molecular Formula]
C6H5BClFO2 | [MDL Number]
MFCD05664225 | [Molecular Weight]
174.37 | [MOL File]
352535-83-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
122-127 °C (lit.) | [Boiling point ]
310.8±52.0 °C(Predicted) | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
powder to crystal | [pka]
7.35±0.58(Predicted) | [color ]
White to Almost white | [InChI]
1S/C6H5BClFO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,10-11H | [InChIKey]
GGTUVWGMCFXUAS-UHFFFAOYSA-N | [SMILES]
OB(O)c1cc(Cl)ccc1F | [CAS DataBase Reference]
352535-83-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-37-60 | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29319090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral |
| Hazard Information | Back Directory | [Uses]
Reactant involved in:
- Suzuki cross-coupling reactions
- Synthesis of biaryl amides with muscarinic acetylcholine receptor subtype M1 agonistic activity
- Synthesis of kinesin spindle protein inhibitors
- GABA α2/3 agonist preparation
| [Uses]
suzuki reaction | [Synthesis]
To a solution of 2-bromo-4-chloro-1-fluorobenzene (5 g, 0.0238 mol) in anhydrous ether (30 ) at -70°C under nitrogen atmosphere was added a 2M solution of n-BuLi in hexane (13 mL, 0.0262 mol).
mL) in anhydrous ether (30 ) was added to a 2 M solution of n- |
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