| Identification | Back Directory | [Name]
MS7972 | [CAS]
352553-42-5 | [Synonyms]
MS7972
9-Acetyl-2,3,4,9-tetrahydro-1H-carbazol-1-one
1H-Carbazol-1-one, 9-acetyl-2,3,4,9-tetrahydro-
inhibit,Inhibitor,MDM-2/p53,MS-7972,MS7972,MS 7972 | [Molecular Formula]
C14H13NO2 | [MDL Number]
MFCD00228962 | [MOL File]
352553-42-5.mol | [Molecular Weight]
227.26 |
| Chemical Properties | Back Directory | [Boiling point ]
399.0±11.0 °C(Predicted) | [density ]
1.28±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (440.02 mM; Need ultrasonic) | [form ]
Solid | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
MS7972 is a small molecule that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM[1]. | [References]
[1] Sachchidanand, et al. Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chem Biol. 2006 Jan;13(1):81-90. DOI:10.1016/j.chembiol.2005.10.014 |
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| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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