| Identification | Back Directory | [Name]
FTLSLDVPTNIMNILFNIDKAKNLRAKAAANAQLMAQI-NH2 | [CAS]
357952-10-4 | [Synonyms]
UCN-II
UCN-II MOUSE
SCP (3-40) (MOUSE)
UROCORTIN III (MOUSE)
Stresscopin (3-40) (mouse)
UCN III (MOUSE) TRIFLUOROACETATE SALT
SCP (3-40) (MOUSE) TRIFLUOROACETATE SALT
FTLSLDVPTNIMNILFNIDKAKNLRAKAAANAQLMAQI-NH2
UROCORTIN III (MOUSE) TRIFLUOROACETATE SALT
STRESSCOPIN (3-40) (MOUSE) TRIFLUOROACETATE SALT
Stresscopin (3-40) (Mouse), SCP (3-40) (Mouse), Ucn III (Mouse)
Urocortin III, mouse FTLSLDVPTNIMNILFNIDKAKNLRAKAAANAQLMAQI-NH2
PHE-THR-LEU-SER-LEU-ASP-VAL-PRO-THR-ASN-ILE-MET-ASN-ILE-LEU-PHE-ASN-ILE-ASP-LYS-ALA-LYS-ASN-LEU-ARG-ALA-LYS-ALA-ALA-ALA-ASN-ALA-GLN-LEU-MET-ALA-GLN-ILE-NH2
VAL-ILE-LEU-SER-LEU-ASP-VAL-PRO-ILE-GLY-LEU-LEU-ARG-ILE-LEU-LEU-GLU-GLN-ALA-ARG-TYR-LYS-ALA-ALA-ARG-ASN-GLN-ALA-ALA-THR-ASN-ALA-GLN-ILE-LEU-ALA-HIS-VAL-NH2
H-PHE-THR-LEU-SER-LEU-ASP-VAL-PRO-THR-ASN-ILE-MET-ASN-ILE-LEU-PHE-ASN-ILE-ASP-LYS-ALA-LYS-ASN-LEU-ARG-ALA-LYS-ALA-ALA-ALA-ASN-ALA-GLN-LEU-MET-ALA-GLN-ILE-NH2
H-Val-Ile-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Arg-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Tyr-Lys-Ala-Ala-Arg-Asn-Gln-Ala-Ala-Thr-Asn-Ala-Gln-Ile-Leu-Ala-His-Val-NH2 | [Molecular Formula]
C186H312N52O52S2 | [MDL Number]
MFCD03792655 | [MOL File]
357952-10-4.mol | [Molecular Weight]
4172.91 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [solubility ]
Soluble in DMSO | [form ]
solid
| [Sequence]
Phe-Thr-Leu-Ser-Leu-Asp-Val-Pro-Thr-Asn-Ile-Met-Asn-Ile-Leu-Phe-Asn-Ile-Asp-Lys-Ala-Lys-Asn-Leu-Arg-Ala-Lys-Ala-Ala-Ala-Asn-Ala-Gln-Leu-Met-Ala-Gln-Ile-NH2 |
| Hazard Information | Back Directory | [Uses]
Urocortin III, mouse is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2[1]. Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in the medial amygdala regulate complex social dynamics[2]. | [storage]
Store at -20°C | [References]
[1] Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7570-5. Lewis K, et al. Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor. Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor. DOI:10.1073/pnas.121165198
[2] Shemesh Y, et al. Ucn3 and CRF-R2 in the medial amygdala regulate complex social dynamics. Nat Neurosci. 2016 Nov;19(11):1489-1496. DOI:10.1038/nn.4346 |
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Sigma-Aldrich
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