| Identification | More | [Name]
Halofantrine hydrochloride | [CAS]
36167-63-2 | [Synonyms]
1,3-dichloro-alpha-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)-9-phenathrenemethanol hydrochloride
halofantrine hydrochloride
1,3-dichloro-alpha-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)phenanthren-1-methanol hydrochloride
Halofantarine HCL
Halfan, 1,3-Dichloro-a-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)-9-phenanthrenemethanol hydrochloride
Halfan | [EINECS(EC#)]
252-895-4 | [Molecular Formula]
C26H30Cl2F3NO.HCl;C26H31Cl3F3NO | [MDL Number]
MFCD00879136 | [MOL File]
36167-63-2.mol | [Molecular Weight]
536.88 |
| Chemical Properties | Back Directory | [Melting point ]
93-96°; mp 203-204° | [storage temp. ]
2-8°C | [solubility ]
DMSO: >10mg/mL | [form ]
solid | [color ]
white to off-white | [Major Application]
pharmaceutical (small molecule) | [InChI]
1S/C26H30Cl2F3NO.ClH/c1-3-5-10-32(11-6-4-2)12-9-25(33)23-16-22-21(14-18(27)15-24(22)28)20-13-17(26(29,30)31)7-8-19(20)23;/h7-8,13-16,25,33H,3-6,9-12H2,1-2H3;1H | [InChIKey]
WANGFTDWOFGECH-UHFFFAOYSA-N | [SMILES]
Cl.CCCCN(CCCC)CCC(O)c1cc2c(Cl)cc(Cl)cc2c3cc(ccc13)C(F)(F)F | [CAS DataBase Reference]
36167-63-2(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Antimalarial. | [Brand name]
Halfan (GlaxoSmithKline). | [Biological Activity]
Halofantrine is a blocker of delayed rectifier potassium current via the inhibition of hERG channel. | [IC 50]
Plasmodium |
| Safety Data | Back Directory | [WGK Germany ]
3 | [RTECS ]
SF7790000 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Aquatic Chronic 4 |
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