| Identification | Back Directory | [Name]
5-(10H-Phenothiazin-10-ylcarbonyl)-2(1H)-pyridinone | [CAS]
366448-34-2 | [Synonyms]
Serine Hydrolase inhibitor-21
5-(10H-Phenothiazin-10-ylcarbonyl)-2(1H)-pyridinone
(6-Hydroxy-pyridin-3-yl)-phenothiazin-10-yl-methanone | [Molecular Formula]
C18H12N2O2S | [MOL File]
366448-34-2.mol | [Molecular Weight]
320.37 |
| Chemical Properties | Back Directory | [Boiling point ]
558.1±50.0 °C(Predicted) | [density ]
1.408±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Solid | [pka]
9.60±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Serine Hydrolase inhibitor-21 (compound 8), a pyridine, is a serine hydrolase inhibitor with a Ki of 429 nM for BuChE. Serine Hydrolase inhibitor-21 has the potential for Alzheimer's disease research[1]. | [References]
[1] Sultan Darvesh, et al. Novel pyridones and their use as modulators of serine hydrolase enzymes. WO2001077078A1. |
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