| Identification | More | [Name]
4-HYDROXY-6-(TRIFLUOROMETHYL)PYRIMIDINE-2-THIOL | [CAS]
368-54-7 | [Synonyms]
2-MERCAPTO-4-HYDROXY-6-TRIFLUOROMETHYLPYRIMIDINE
2-MERCAPTO-6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL
2-SULFANYL-6-(TRIFLUOROMETHYL)-4-PYRIMIDINOL
4-HYDROXY-2-MERCAPTO-6-(TRIFLUOROMETHYL)PYRIMIDINE
4-HYDROXY-6-(TRIFLUOROMETHYL)PYRIMIDINE-2-THIOL
6-HYDROXY-2-MERCAPTO-4-TRIFLUOROMETHYLPYRIMIDINE
6-(TRIFLUOROMETHYL)-2-THIOURACIL
BUTTPARK 6\01-78
IFLAB-BB F2124-0845
URACIL, 2-THIO-6-(TRIFLUOROMETHYL)-
4(1H)-Pyrimidinone, 2,3-dihydro-2-thioxo-6-(trifluoromethyl)-
6-(trifluoromethyl)-2-mercaptopyrimidin-4-ol
4-Hydroxy-6-(trifluoromethyl)pyrimidine-2-thiol, 97+% | [Molecular Formula]
C5H3F3N2OS | [MDL Number]
MFCD00112978 | [Molecular Weight]
196.15 | [MOL File]
368-54-7.mol |
| Questions And Answer | Back Directory | [Uses]
4-Hydroxy-6-(trifluoromethyl)pyrimidine-2-thiol is a pyrimidine derivative that can be used to prepare drugs for cancer treatment, antibacterial activity, antimalarial treatment, and arthritis treatment; it can also be used in the synthesis of herbicides, insecticides, and fungicides. For example, the antimalarial drug pyrimethamine, the antihypertensive drug minoxidil, the anticancer drug 5-fluorouracil, and the pesticide fungicides ethirimol and methylpyrimethanil all contain pyrimidine structures. |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29335990 | [Storage Class]
11 - Combustible Solids |
| Hazard Information | Back Directory | [General Description]
4-Hydroxy-6-(trifluoromethyl)pyrimidine-2-thiol (HTPT) can form a stable monolayer on the Au(111) surface. | [Synthesis]
A 250mL three-necked flask equipped with mechanical stirring and a reflux condenser tube was charged with 27.6g (0.15 mol) ethyl trifluoroacetoacetate, 11.4g (0.15 mol) thiourea,100 mLDMF, heated to 120°C, and the reaction was carried out for 4 hours. Coo |
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