| Identification | More | [Name]
METHYL CAFFEATE | [CAS]
3843-74-1 | [Synonyms]
3,4-DIHYDROXYCINNAMIC ACID METHYL ESTER
CAFFEIC ACID METHYL ESTER
METHYL 3,4-DIHYDROXYCINNAMATE
METHYL CAFFEATE
TIMTEC-BB SBB000325
3-(3,4-Dihydroxyphenyl)acrylic acid methyl ester
3-(3,4-Dihydroxyphenyl)propenoic acid methyl ester
Caffeic acid methyl
Maritin E
Methyl caffeoate | [Molecular Formula]
C10H10O4 | [MDL Number]
MFCD00210468 | [Molecular Weight]
194.18 | [MOL File]
3843-74-1.mol |
| Chemical Properties | Back Directory | [Appearance]
slightly yellowish solid | [Melting point ]
158-161°C | [Boiling point ]
368℃ | [density ]
1.318 | [refractive index ]
1.5168 (estimate) | [Fp ]
80 °C
| [storage temp. ]
0-6°C | [solubility ]
Acetonitrile (Slightly), Dimethylformamide, DMSO, Ethyl Acetate, Methanol (Slightly) | [form ]
Solid | [pka]
8.71±0.18(Predicted) | [color ]
Off-White to Brown | [λmax]
328nm(MeOH)(lit.) | [Stability:]
Light Sensitive | [LogP]
1.190 (est) | [CAS DataBase Reference]
3843-74-1(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
Caffeic acid methyl ester is an ester of a naturally occurring phenolic compound found in P. amplexicaule var. sinense and S. torvum fruits. At 40 mg/kg, it demonstrates antihyperglycemic and antidiabetic activity in diabetic rats, upregulating GLUT4 and regenerating pancreatic β-cells.1 At 10 mg/kg, it can induce anti-inflammatory and antinociceptive effects in rat models of edema and pain, inhibiting nitric oxide and prostaglandin E2 production, as well as tumor necrosis factor-α release.2 | [Chemical Properties]
slightly yellowish solid | [Uses]
Inhibitor of protein tyrosine kinase | [Definition]
ChEBI: An alkyl caffeate ester formed by the formal condensation of caffeic acid with methyl alcohol. | [storage]
Store at -20°C | [References]
[1] GOPALSAMY RAJIV GANDHI . Antihyperglycemic activity and antidiabetic effect of methyl caffeate isolated from Solanum torvum Swartz. fruit in streptozotocin induced diabetic rats[J]. European journal of pharmacology, 2011, 670 2: Pages 623-631. DOI: 10.1016/j.ejphar.2011.09.159
[2] KYUNG-MIN SHIN . Anti-inflammatory effect of caffeic acid methyl ester and its mode of action through the inhibition of prostaglandin E2, nitric oxide and tumor necrosis factor-α production[J]. Biochemical pharmacology, 2004, 68 12: Pages 2327-2336. DOI: 10.1016/j.bcp.2004.08.002 |
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| Company Name: |
Rhawn Reagent
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| Telephone: |
400-400-1332688 18019345275 |
| Website: |
http://www.rhawn.cn |
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