| Identification | Back Directory | [Name]
Epibetulinic acid | [CAS]
38736-77-5 | [Synonyms]
Epibetulinicaci
Epibetulinic acid
3-epi-Betulinic acid
alpha-Betulinic acid
3α-Hydroxylup-20(29)-en-28-oic acid
(3alpha)-3-Hydroxy-lup-20(29)-en-28-oic acid | [Molecular Formula]
C30H48O3 | [MDL Number]
MFCD09953801 | [MOL File]
38736-77-5.mol | [Molecular Weight]
456.7 |
| Chemical Properties | Back Directory | [Melting point ]
277℃ | [Boiling point ]
550.0±33.0 °C(Predicted) | [density ]
1.065 | [storage temp. ]
Sealed in dry,2-8°C | [form ]
Solid | [pka]
4.61±0.70(Predicted) | [color ]
White to off-white | [InChIKey]
QGJZLNKBHJESQX-SPTQAKTHNA-N | [SMILES]
[C@@]12(C)CC[C@]3([C@]([H])([C@H](C(C)=C)CC3)[C@@]1([H])CC[C@]1([H])[C@@]3([C@]([H])(C(C)(C)[C@H](CC3)O)CC[C@@]21C)C)C(O)=O |&1:0,4,5,7,13,17,19,20,25,31,r| |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from sour jujube seeds and lotus root node charcoal. | [Uses]
Epibetulinic Acid exhibits a strong anti-HIV activity. Isolated from the stem bark of Dillenia indica Linn. Also, it can be a potent and selective TGR5 agonists with improved cellular efficacy. | [IC 50]
NO: 0.7 μM (IC50); EP2: 0.6 μM (IC50) |
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