| Identification | Back Directory | [Name]
2-Naphthaleneacetamide, N-[1-[cis-3-(acetylamino)cyclobutyl]-1H-imidazol-4-yl]- | [CAS]
395074-72-3 | [Synonyms]
CDK2-IN-1
2-Naphthaleneacetamide, N-[1-[cis-3-(acetylamino)cyclobutyl]-1H-imidazol-4-yl]- | [Molecular Formula]
C21H22N4O2 | [MDL Number]
MFCD34471145 | [MOL File]
395074-72-3.mol | [Molecular Weight]
362.42 |
| Chemical Properties | Back Directory | [Boiling point ]
772.5±60.0 °C(Predicted) | [density ]
1.31±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (275.92 mM; Need ultrasonic) | [form ]
Solid | [pka]
13.52±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a. GSK-3/CDK5/CDK2-IN-1 can be used for the research of cancer, and neurodegenerative diseases[1]. | [References]
[1] Ahlijanian MK, et, al. Preparation of acylaminoimidazoles as inhibitors of cdk5, cdk2, and GSK-3. WO2002010141A1. |
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