| Identification | Back Directory | [Name]
N-Acetyl-1,3-propanediamine | [CAS]
4078-13-1 | [Synonyms]
N-Acetyl-1,3-propanediamine
Acetamide, N-(3-aminopropyl)- | [Molecular Formula]
C5H12N2O | [MDL Number]
MFCD09863401 | [MOL File]
4078-13-1.mol | [Molecular Weight]
116.16 |
| Chemical Properties | Back Directory | [Boiling point ]
130 °C(Press: 3 Torr) | [density ]
0.9879 g/cm3 | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [solubility ]
Chloroform, Ethyl Acetate | [pka]
16.30±0.46(Predicted) |
| Hazard Information | Back Directory | [Description]
N-(3-Aminopropyl)acetamide is a monoacetylated polyamine that can be used as a building block in the synthesis of heterocyclic compounds. Polyamines are promising biochemical markers of cancer and many other pathophysiological conditions, thus their concentrations in biological fluids have been analyzed. | [Uses]
N-Acetyl-1,3-propanediamine is an protected intermediate in the synthesis of analogs of Spermidine (S680400), an antineoplastic agent. | [Definition]
ChEBI: N-monoacetylalkane-alpha,omega-diamine is an acetamide obtained by acetylation of one of the amino groups of any alkane-alpha,omega-diamine. AcNHCH2(CH2)nCH2NH2, where n = 0, 1, 2, etc. It is a member of acetamides and a primary amino compound. It is functionally related to an alkane-alpha,omega-diamine. It is a conjugate base of a N-monoacetylalkane-alpha,omega-diamine(1+). | [References]
[1] MERJA R. H?KKINEN . Analysis of free, mono- and diacetylated polyamines from human urine by LC–MS/MS[J]. Journal of Chromatography B, 2013, 941: Pages 81-89. DOI: 10.1016/j.jchromb.2013.10.009 |
|
|