| Identification | Back Directory | [Name]
4'-METHOXYFLAVONE | [CAS]
4143-74-2 | [Synonyms]
4'-METHOXYFLAVONE
METHOXYFLAVONE, 4'-
2-(4-methoxyphenyl)chromone
2-(4-methoxyphenyl)-4-benzopyrone
2-(4-Methoxy-phenyl)-chromen-4-one
4' METHOXYFLAVONE,4'METHOXYFLAVONE
2-(4-methoxyphenyl)-4h-1-benzopyran-4-on
2-(4-Methoxyphenyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one,2-(4-methoxyphenyl)- | [EINECS(EC#)]
223-968-8 | [Molecular Formula]
C16H12O3 | [MDL Number]
MFCD00016934 | [MOL File]
4143-74-2.mol | [Molecular Weight]
252.26 |
| Hazard Information | Back Directory | [Uses]
4'-Methoxyflavone is a flavonoid with antioxidant properties and anti-proliferative activity against cancer cells. 4'-Methoxyflavone can inhibit cycle-dependent kinases leading to cell cycle arrest and regulate cell signaling pathways to influence cell proliferation and apoptosis. 4'-Methoxyflavone can be used in cancer chemoprevention research[1]. | [Definition]
ChEBI:2-(4-methoxyphenyl)-1-benzopyran-4-one is a member of flavonoids and an ether. | [Biological Activity]
4-methoxyflavone is a neuroprotective agent th at inhibits the accumulation of poly (ADP-ribose) and neuronal cell death following chemically-induced DNA damage or NMDA excitation. | [References]
[1] Walle U K, et al. Bioavailable flavonoids: cytochrome P450-mediated metabolism of methoxyflavones[J]. Drug Metabolism and Disposition, 2007, 35(11): 1985-1989. DOI:10.1124/dmd.107.016782 |
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