| Identification | Back Directory | [Name]
Bendamustine Desmethyl Impurity | [CAS]
41515-13-3 | [Synonyms]
Bendamustine M4
BendamustineImpurity5-d4
N-desmethyl Bendamustine
4-(5-(bis(2-chloroethyl)amino)-1H
Bendamustine Impurity 5 (Desmethyl Impurity)
N-Desmethylbendamustine trifluoroacetate salt
1H-Benzimidazole-2-butanoic acid, 6-[bis(2-chloroethyl)amino]-
Bendamustine impurity 10/Desmethyl Bendamustine/6-[Bis(2-chloroethyl)amino]-1H-Benzimidazole-2-butanoic Acid | [Molecular Formula]
C15H19Cl2N3O2 | [MOL File]
41515-13-3.mol | [Molecular Weight]
344.24 |
| Hazard Information | Back Directory | [Description]
N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine (Item No. 23693).1 N-desmethyl Bendamustine is formed through demethylation of the benzimidazole ring in bendamustine by the cytochrome P450 (CYP) isoform CYP1A2. It inhibits proliferation of non-cancerous peripheral blood leukocytes (PBLs; IC50 = 45 µM) and SU-DHL-1, SU-DHL-9, and Daudi lymphoma cells (IC50s = 270, 170, and 120 µM, respectively).WARNING This product is not for human or veterinary use. | [storage]
Store at -20°C |
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| Company Name: |
TOSUN PHARM
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| Tel: |
020-61855200 13326451905 |
| Website: |
www.toref.cn/ |
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