| Identification | More | [Name]
Cbz-N-methyl-L-valine | [CAS]
42417-65-2 | [Synonyms]
BENZYLOXYCARBONYL-N-ALPHA-METHYL-L-VALINE
BENZYLOXYCARBONYL-N-METHYL-L-VALINE
N-ALPHA-BENZYLOXYCARBONYL-N-ALPHA-METHYL-L-VALINE
N-ALPHA-CARBOBENZOXY-N-ALPHA-METHYL-L-VALINE
N-ALPHA-CBZ-N-ALPHA-METHYL-L-VALINE
N-BENZYLOXYCARBONYL-N-METHYL-L-VALINE
Z-L-MEVAL-OH
Z-METHYL-L-VALINE
Z-MEVAL-OH
Z-N-METHYL-L-VALINE
Z-N-ME-VALINE
Z-N-ME-VAL-OH
Cbz-N-D-Me-Val-OH
Z-N-ME-VAL 98.5+%
CBZ-N-ME-VAL-OH
NALPHA-Benzyloxycarbonyl-N-methyl-L-valine
Cbz-N-methyl-L-valine
CBZ-N-.ALPHA.-METHYL-L-VALINE | [Molecular Formula]
C14H19NO4 | [MDL Number]
MFCD00153397 | [Molecular Weight]
265.3 | [MOL File]
42417-65-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
68-70 °C(lit.) | [Boiling point ]
407.1±34.0 °C(Predicted) | [density ]
1.166±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT. | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
Crystalline Solid | [pka]
4.01±0.10(Predicted) | [color ]
White | [Major Application]
peptide synthesis | [InChI]
1S/C14H19NO4/c1-10(2)12(13(16)17)15(3)14(18)19-9-11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3,(H,16,17)/t12-/m0/s1 | [InChIKey]
NNEHOKZDWLJKHP-LBPRGKRZSA-N | [SMILES]
CC(C)[C@H](N(C)C(=O)OCc1ccccc1)C(O)=O | [CAS DataBase Reference]
42417-65-2(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
(S)-N-(Benzyloxycarbonyl)-N-methylvaline has been used as a reactant in the synthesis of a biologically active cyclodepsipeptide destruxin E which is a potent negative regulator of osteoclast morphology. | [reaction suitability]
reaction type: solution phase peptide synthesis | [Synthesis]
Under argon atmosphere, 60% sodium hydroxide (5 g, 0.125 mol) was added in one portion to a stirred mixture of Cbz-L-valine (9.5 g, 0.038) in anhydrous THF (150 mL) at 0°C and stirred simultaneously for 30 minutes.
mol) in anhydrous THF (150 mL) and stir |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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