| Identification | More | [Name]
4-Fluoro-2-methylphenol | [CAS]
452-72-2 | [Synonyms]
2-METHYL-4-FLUOROPHENOL
4-FLUORO-2-METHYLPHENOL
4-FLUORO-O-CRESOL
4-Fluoro-o-methylphenol
4-Fluoro-2-methylphenol 99%
4-Fluoro-2-methylphenol99% | [EINECS(EC#)]
207-209-8 | [Molecular Formula]
C7H7FO | [MDL Number]
MFCD00075088 | [Molecular Weight]
126.13 | [MOL File]
452-72-2.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-white to brownish low melting solid or liquid | [Melting point ]
37-38 °C (lit.) | [Boiling point ]
87 °C/14 mmHg (lit.) | [density ]
1.1514 (estimate) | [refractive index ]
1.5155-1.5175
| [Fp ]
185 °F
| [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
Low Melting Solid or Liquid | [pka]
10.32±0.18(Predicted) | [color ]
Off-white to brownish | [Water Solubility ]
Insoluble in water. | [BRN ]
2041490 | [InChI]
InChI=1S/C7H7FO/c1-5-4-6(8)2-3-7(5)9/h2-4,9H,1H3 | [InChIKey]
GKQDDKKGDIVDAG-UHFFFAOYSA-N | [SMILES]
C1(O)=CC=C(F)C=C1C | [CAS DataBase Reference]
452-72-2(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R21/22:Harmful in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN 1325 4.1/PG 2
| [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
8 | [HazardClass ]
IRRITANT | [HS Code ]
29081990 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-white to brownish low melting solid or liquid | [Uses]
4-Fluoro-2-methylphenol is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields. | [General Description]
Laccase mediated grafting of 4-fluoro-2-methylphenol with lignin model compound, dibenzodioxocin and lignocellulose material has been investigated. | [Synthesis]
Add 70g of water and 26g of concentrated sulfuric acid to the 250mL reaction flask (pay attention to exothermic, add concentrated sulfuric acid to water slowly, the same below), add 17.5g of 4-fluoro-2-methylaniline at room temperature while stirring, a w | [References]
[1] Tetrahedron Letters, 2011, vol. 52, # 41, p. 5338 - 5341 |
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