| Identification | Back Directory | [Name]
BENZ[G]ISOQUINOLINE-5,10-DIONE | [CAS]
46492-08-4 | [Synonyms]
Bgid
Biquidone
Nsc 338695
2-Azaanthraquinone
3,4-Phthaloylpyridine
β-Anthrapyridinequinone
2-aza-9,10-anthraquinone
BENZ[G]ISOQUINOLINE-5,10-DIONE
benzo(g)isoquinoline-5,10-dione
Benz[g]isoquinoline-5,10-dione 99%
5,10-Dihydrobenzo[g]isoquinoline-5,10-dione
Benz[g]isoquinoline-5,10-dione | [Molecular Formula]
C13H7NO2 | [MDL Number]
MFCD00010399 | [MOL File]
46492-08-4.mol | [Molecular Weight]
209.2 |
| Chemical Properties | Back Directory | [Melting point ]
178-180 °C(lit.) | [Boiling point ]
407℃ | [density ]
1.373 | [Fp ]
202℃ | [pka]
1.10±0.20(Predicted) | [InChI]
1S/C13H7NO2/c15-12-8-3-1-2-4-9(8)13(16)11-7-14-6-5-10(11)12/h1-7H | [InChIKey]
ZLLVUAAESHIVAZ-UHFFFAOYSA-N | [SMILES]
O=C1c2ccccc2C(=O)c3cnccc13 |
| Hazard Information | Back Directory | [Uses]
Benz[g]isoquinoline-5,10-dione, an active component isolated from the ethanolic extract of the aerial parts of Mitracarpus scaber, demonstrates notable in vitro inhibitory activity against AIDS-related pathogens, along with significant antibacterial and antifungal properties, as evidenced by the agar well-diffusion assay. | [General Description]
Benz[g]isoquinoline-5,10-dione has been isolated as an active component from the ethanolic extract of the aerial parts of Mitracarpus scaber. It exhibits significant in vitro inhibitory activity against the AIDS-related pathogens. The in vitro antibacterial and anti-fungal activity of benz[g]isoquinoline-5,10-dione has been investigated using the agar well-diffusion assay. | [References]
[1] Quantitative determination of lysophosphatidic acid by LC/ESI/MS/MS employing a reversed phase HPLC column
[2] Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis
[3] Lysophosphatidic acid triggers apoptosis in HeLa cells through the upregulation of tumor necrosis factor receptor superfamily member 21
[4] Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis |
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