| Identification | Back Directory | [Name]
GLY-LEU-MET-NH2 | [CAS]
4652-64-6 | [Synonyms]
GLY-LEU-MET-NH2
9-11-Substance P
SUBSTANCE P (9-11)
Gly-L-Leu-L-Met-NH2
SUBSTANCE P FRAGMENT 9-11
Substance-p-tripepide(9-11)
L-Methioninamide, glycyl-L-leucyl- | [Molecular Formula]
C13H26N4O3S | [MDL Number]
MFCD00080136 | [MOL File]
4652-64-6.mol | [Molecular Weight]
318.44 |
| Chemical Properties | Back Directory | [Melting point ]
156-158 °C | [Boiling point ]
651.2±55.0 °C(Predicted) | [density ]
1.159±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [pka]
13.38±0.46(Predicted) |
| Hazard Information | Back Directory | [Uses]
Gly-Leu-Met-NH2 is a C-terminal tripeptide of Substance P (Substance P (HY-P0201)). Substance P is a neuropeptide[1]. | [Definition]
ChEBI: Gly-L-Leu-L-Met-NH2 is a tripeptide composed of glycine, L-leucine and L-methioninamide joined in sequence by peptide linkages. It is a C-terminal fragment of substance P. It is functionally related to a glycine, a L-leucine and a L-methioninamide. It is a conjugate base of a Gly-L-Leu-L-Met-NH2(1+). | [References]
[1] Sandrine Sagan, et al. Conformational analysis of the C-terminal Gly-Leu-Met-NH2 tripeptide of substance P bound to the NK-1 receptor. Chem Biol. 2005 May;12(5):555-65. DOI:10.1016/j.chembiol.2005.03.005 |
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