| Identification | Back Directory | [Name]
2-Mercapto-2-phenylacetic acid | [CAS]
4695-09-4 | [Synonyms]
Thiomandelic acid
Mercaptophenylacetic acid
α-Mercaptobenzeneacetic acid
2-phenyl-2-sulfanylacetic acid
2-Mercapto-2-phenylacetic acid | [Molecular Formula]
C8H8O2S | [MDL Number]
MFCD11109159 | [MOL File]
4695-09-4.mol | [Molecular Weight]
168.21 |
| Chemical Properties | Back Directory | [Melting point ]
64-65 °C | [Boiling point ]
145 °C(Press: 4 Torr) | [density ]
1.277±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.21±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Thiomandelic acid is an Anti-Bacterial Agent. | [Uses]
Thiomandelic acid is a broad spectrum inhibitor of Zinc -lactamases[1]. | [References]
[1] C Mollard, et al. Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies. J Biol Chem. 2001 Nov 30;276(48):45015-23. DOI:10.1074/jbc.M107054200
[2] Christian Damblon, et al. The inhibitor thiomandelic acid binds to both metal ions in metallo-beta-lactamase and induces positive cooperativity in metal binding. J Biol Chem. 2003 Aug 1;278(31):29240-51. DOI:10.1074/jbc.M301562200 |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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