| Identification | More | [Name]
1,4-Cineole | [CAS]
470-67-7 | [Synonyms]
1,4-CINEOLE 1-ISOPROPYL-4-METHYL-7-OXABICYCLO[2.2.1]HEPTANE 1-Methyl-4-(1-methylethyl)-7-oxabicyclo[2.2.1]heptane CINEOLE, 1,4- FEMA 3658 ISOCINEOLE 1,4-cineol 1,4-epoxy-p-menthan 1,4-Epoxy-p-menthane 1-isopropyl-4-methyl-7-oxabicyclo(2.2.1)heptan 1-methyl-4-(1-methylethyl)-7-oxabicyclo(2.2.1)heptan 1-methyl-4-(1-methylethyl)-7-oxabicyclo[2.2.1]heptan 7-Oxabicyclo(2.2.1)heptane, 1-isopropyl-4-methyl- 7-Oxabicyclo[2.2.1]heptane, 1-methyl-4-(1-methylethyl)- p-Menthane, 1,4-epoxy 1,4-cineol, mixture of isomers 1,4-CINEOLE, TERPENE STANDARD 1,4-cineole,1-methyl-4-(1-methylethyl)-7-oxabicyclo[2.2.1]heptane,isocineole,1,4-epoxy-p-menthane CINEOLE, 1,4-(SG) CINEOL 1,4 | [EINECS(EC#)]
207-428-9 | [Molecular Formula]
C10H18O | [MDL Number]
MFCD00209502 | [Molecular Weight]
154.25 | [MOL File]
470-67-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
-46 °C (lit.) | [Boiling point ]
65 °C/16 mmHg (lit.) | [density ]
0.887 g/mL at 25 °C(lit.)
| [FEMA ]
3658 | [refractive index ]
n20/D 1.445(lit.)
| [Fp ]
118 °F
| [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 125 mg/mL (810.37 mM) | [Water Solubility ]
Slightly soluble in water | [form ]
neat | [color ]
Colorless to Almost colorless | [Odor]
at 10.00 % in dipropylene glycol. cooling pine minty camphor terpene green | [biological source]
synthetic | [Odor Type]
herbal | [JECFA Number]
1233 | [BRN ]
104974 | [Cosmetics Ingredients Functions]
PERFUMING SKIN PROTECTING | [LogP]
2.97 | [CAS DataBase Reference]
470-67-7(CAS DataBase Reference) | [NIST Chemistry Reference]
7-Oxabicyclo[2.2.1]heptane, 1-methyl-4-(1-methylethyl)-(470-67-7) | [EPA Substance Registry System]
470-67-7(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
1,4-Cineole has a light and mild camphoraceous odor and a cool, mildly spice-like flavor. | [Occurrence]
Reported present in Piper cubeba, lime peel oil, apricot, cardamom (Eleteria cardamomun Maton), orange
juice, grapefruit juice, laurel (Laurus nobilis L), rosemary and mastic gum leaf oil. It is also present in various essential oils; Boldea
fragrans Juss., Xanthoxylum rhetsa D.C. and Ormenis multicaulis. | [Uses]
Apart from the academic interest related to the olfactory similarity or dissimilarity) of isomer chemicals, there is not much interest in this chemical. It is not nearly as readily available as its isomer, Eucalyptol. | [Definition]
ChEBI: 1,4-cineole is an oxabicycloalkane consisting of p-menthane with an epoxy bridge across positions 1 and 4. It has a role as a plant metabolite, a fumigant insecticide and a central nervous system depressant. It is a cineole and an oxabicycloalkane. | [Taste threshold values]
Taste characteristics at 40 ppm: cooling, minty, menthol-like, green and herbal, with a terpy and camphoraceous
nuance. | [General Description]
1,4-Cineole is present in eucalyptus oil. It activated both human TRPA1 (a sensor of noxious cold) and human TRPM 8 (a thermosensitive receptor). It is a natural monoterpene that inhibits plant growth. | [Synthesis]
Its structure has been confirmed through synthesis.* | [storage]
Store at -20°C |
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