ChemicalBook--->CAS DataBase List--->473722-68-8

473722-68-8

473722-68-8 Structure

473722-68-8 Structure
IdentificationBack Directory
[Name]

(±)-NBI 74330
[CAS]

473722-68-8
[Synonyms]

racNBI74330
rac-NBI-74330
rac NBI 74330
N-1-[(3-4(-Ethoxyphenyl)-3,4-dihydro-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-4-fluoro-N-(3-pyridinylmethyl)-3-(trifluoromethyl)benzeneacetamide
N-{1-[3-(4-Ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-2-(4-fluoro-3-trifluoromethyl-phenyl)-N-pyridin-3-ylmethyl-acetamide
[Molecular Formula]

C32H27F4N5O3
[MDL Number]

MFCD22665718
[MOL File]

473722-68-8.mol
[Molecular Weight]

605.58
Chemical PropertiesBack Directory
[solubility ]

Soluble to 50 mM in DMSO
Hazard InformationBack Directory
[Uses]

N-?[1-?[3-?(4-Ethoxyphenyl)?-?3,?4-?dihydro-?4-?oxopyrido[2,?3-?d]?pyrimidin-?2-?yl]?ethyl]?-?4-?fluoro-?N-?(3-?pyridinylmethyl)?-?3-?(trifluoromethyl)?-benzeneacetamide is a potent and selective CXCR3 antagonist. CXCR3 is a chemokine receptor involved in many inflammatory diseases including rheumatoid arthritis, multiple sclerosis and psoriasis.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

(±)-NBI 74330(473722-68-8)1HNMR
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