| Identification | Back Directory | [Name]
Amino-PEG9-Amine | [CAS]
474082-35-4 | [Synonyms]
474082-35-4
NH2-PEG9-NH2
Amino-PEG9-Amine
H2N-PEG19-CH2CH2NH2
3,6,9,12,15,18,21,24,27-Nonaoxanonacosane-1,29-diamine
2-{2-[2-(2-{2-[2-(2-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethylamine | [Molecular Formula]
C20H44N2O9 | [MDL Number]
MFCD28122963 | [MOL File]
474082-35-4.mol | [Molecular Weight]
456.57 |
| Chemical Properties | Back Directory | [Boiling point ]
527.4±45.0 °C(Predicted) | [density ]
1.078±0.06 g/cm3(Predicted) | [form ]
Liquid | [pka]
9.04±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
Amino-PEG9-Amine is a PEG linker containing two amine functional groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. | [Uses]
Amino-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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