4753-04-2

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4753-04-2 Structure

Identification	More
[Name] 2'-CHLORO-2'-DEOXYURIDINE
[CAS] 4753-04-2
[Synonyms] NSC 526746 2-CHLORO-2-DEOXYURIDINE 2'-CHLORO-2'-DEOXYURIDINE Uridine, 2'-chloro-2'-deoxy-
[Molecular Formula] C9H11ClN2O5
[MDL Number] MFCD00057379
[Molecular Weight] 262.65
[MOL File] 4753-04-2.mol

Chemical Properties	Back Directory
[Melting point ] 207-212 °C (decomp)
[density ] 1.67±0.1 g/cm3(Predicted)
[storage temp. ] -20°C
[pka] 9.39±0.10(Predicted)
[CAS DataBase Reference] 4753-04-2(CAS DataBase Reference)

Hazard Information	Back Directory
[Uses] 2′-Chloro-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References] [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

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