| Identification | Back Directory | [Name]
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine | [CAS]
477845-12-8 | [Synonyms]
PIM-1 Inhibitor 2
PIM1 Kinase Inhibitor IV
PIM1 Inhibitor 2,PIM 1 Inhibitor 2
4-(3-(4-chlorophenyl)benzo[c]isoxazol-5-yl)pyrimidin-2-amine
4-[3-(4-Chlorophenyl)-2,1-benzisoxazol-5-yl]-2-pyrimidinamine | [Molecular Formula]
C17H11ClN4O | [MOL File]
477845-12-8.mol | [Molecular Weight]
322.75 |
| Chemical Properties | Back Directory | [Boiling point ]
627.1±65.0 °C(Predicted) | [density ]
1.398±0.06 g/cm3(Predicted) | [storage temp. ]
Store at +4°C | [solubility ]
Soluble to 75 mM in DMSO | [form ]
Yellow solid | [pka]
2.98±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Pim-1 Inhibitor 2 acts as a serione/threonine kinase targeting proteins involved in cell proliferation and survical. Potential anti-tumor agent. | [Uses]
Pim-1 is a serine/threonine kinase that targets proteins involved in cell survival and proliferation and has roles in tumorigenesis. Pim-1 inhibitor 2 is a potent Pim-1 inhibitor (Ki = 91 nM) that targets the ATP-binding kinase hinge region.[Cayman Chemical] | [IC 50]
PIM1: 91 nM (Ki) | [storage]
Store at 4°C |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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