| Identification | Back Directory | [Name]
5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[4-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxy-7-methylquinoline-2-carbonyl]amino]-5-oxopentanoic acid | [CAS]
478005-11-7 | [Synonyms]
BX 048 , CID16741348
1-Piperazinepentanoic acid, γ-[[[4-(1-carboxy-1-methylethoxy)-7-methyl-2-quinolinyl]carbonyl]amino]-4-(ethoxycarbonyl)-δ-oxo-
5-(4-ethoxycarbonylpiperazin-1-yl)-4-[[4-(1-hydroxy-2-methyl-1-oxopropan-2-yl)oxy-7-methylquinoline-2-carbonyl]amino]-5-oxopentanoic acid | [Molecular Formula]
C27H34N4O9 | [MOL File]
478005-11-7.mol | [Molecular Weight]
558.58 |
| Hazard Information | Back Directory | [Uses]
(Rac)-BX 048 is a BX 048 racemate. BX 048 is a P2Y12 receptor antagonist. BX 048 inhibits ADP-induced platelet aggregation in human, dog and rat whole blood. BX 048 also inhibits Arachidonic acid (HY-109590) induced platelet aggregation (IC50 of 15 μM)[1]. | [IC 50]
P2Y12 Receptor | [References]
[1] Post JM, et al. Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II): pharmacodynamic and pharmacokinetic characterization. Thromb Res. 2008;122(4):533-40. DOI:10.1016/j.thromres.2008.04.009 |
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