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485800-26-8

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485800-26-8 Structure

485800-26-8 Structure
IdentificationBack Directory
[Name]

t-Boc-Cystamine
[CAS]

485800-26-8
[Synonyms]

Boc-Cystamine
t-Boc-Cystamine
tert-Butyl 2-[2-(2-aminoethyl)disulfanyl]ethylcarbamate
tert-butyl (2-((2-aminoethyl)disulfanyl)ethyl)carbamate
Carbamic acid, N-[2-[(2-aminoethyl)dithio]ethyl]-, 1,1-dimethylethyl ester
[Molecular Formula]

C9H20N2O2S2
[MDL Number]

MFCD19443372
[MOL File]

485800-26-8.mol
[Molecular Weight]

252.4
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to light yellow
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Corrosion (GHS05)
GHS07,GHS05
[Signal word ]

Danger
[Hazard statements ]

H315-H332-H312-H302-H335-H318
[Precautionary statements ]

P261-P271-P304+P340-P312-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P280-P305+P351+P338-P310-P280-P302+P352-P312-P322-P363-P501
Hazard InformationBack Directory
[Chemical Properties]

T-Boc-Cystamine is a cleavable ADC linker that can be used to synthesize antibody-drug conjugates (ADCs).
[Uses]

Boc-Cystamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
[in vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[target]

Cleavable

[IC 50]

Disulfide Cleavable Linker; Cleavable Linker
[References]

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
Spectrum DetailBack Directory
[Spectrum Detail]

t-Boc-Cystamine(485800-26-8)1HNMR
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