| Identification | Back Directory | [Name]
DC_517 | [CAS]
500017-70-9 | [Synonyms]
DC_517
CS-2082
DC_517
(DC-517)
2-Propanol, 1-[2-(9H-carbazol-9-yl)-1-(9H-carbazol-9-ylmethyl)ethoxy]-3-[(1-methylethyl)amino]- | [Molecular Formula]
C33H35N3O2 | [MDL Number]
MFCD03085270 | [MOL File]
500017-70-9.mol | [Molecular Weight]
505.65 |
| Chemical Properties | Back Directory | [Boiling point ]
727.9±60.0 °C(Predicted) | [density ]
1.20±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 50 mg/mL (98.88 mM);Water : < 0.1 mg/mL (insoluble) | [form ]
Solid | [pka]
13.88±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
DC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 1.7 μM and 0.91 μM, respectively. | [IC 50]
DNMT1: 0.91 μM (Kd); DNMT1: 1.7 μM (IC50) | [storage]
Store at -20°C | [References]
[1] Chen S, et al. Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening. J Med Chem. 2014 Nov 13;57(21):9028-9041. DOI:10.1021/jm501134e |
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Musechem
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+1-800-259-7612 |
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www.musechem.com |
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Cckinase, Inc.
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www.cckinase.com |
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cjbscvictory
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https://www.weikeqi-biotech.com/ |
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