ChemicalBook--->CAS DataBase List--->51012-32-9

51012-32-9

51012-32-9 Structure

51012-32-9 Structure
IdentificationMore
[Name]

Tiapride
[CAS]

51012-32-9
[Synonyms]

LABOTEST-BB LT00772311
TIAPRIDE
flo1347
n-(2-(diethylamino)ethyl)-2-methoxy-5-(methylsulfonyl)-benzamid
N-(Diethylaminoethyl)-2-methoxy-5-methylsulfonyl-benzamide
thiapride
Tiapride hcl
N-[2-Diethylamino ethyl]-5-[methylsufonyl]-o-anisamide
Cyclovirobune D
N-[2-(Diethylamino)ethyl]-2-methoxy-5-(methylsulphonyl)benzamide
N-(2-Diethylaminoethyl)-2-methoxy-5-methylsulfonylbenzamide
N-[2-(Ethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)benzamide
N-[2-(Diethylamino)ethyl]-5-(methylsulfonyl)-2-methoxybenzamide
N-[2-(Diethylamino)ethyl]-5-mesyl-2-methoxybenzamide
[EINECS(EC#)]

256-907-9
[Molecular Formula]

C15H24N2O4S
[MDL Number]

MFCD00242730
[Molecular Weight]

328.43
[MOL File]

51012-32-9.mol
Chemical PropertiesBack Directory
[Melting point ]

123-125°
[vapor pressure ]

0Pa at 25℃
[storage temp. ]

2-8°C
[pka]

9.14[at 20 ℃]
[Water Solubility ]

349mg/L at 25℃
[LogP]

0.9
[CAS DataBase Reference]

51012-32-9(CAS DataBase Reference)
Safety DataBack Directory
[WGK Germany ]

2
[RTECS ]

CV4203800
[REACH Registrations]

Active
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

N-[2-(Diethylamino)ethyl]-2-methoxy-5-(methylsulphonyl)benzamide(51012-32-9).msds
Hazard InformationBack Directory
[Originator]

Tiapridal,Delagrange,France,1977
[Uses]

diuretic, antihypertensive
[Uses]

Tiapride hydrochloride is a D2DR and D3DR inhibitor; Anti-psychotic agent and alternative treatment for Tourette’s syndrome.
[Definition]

ChEBI:N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide is a member of benzamides.
[Manufacturing Process]

5 g of 2-methoxy-5-methylsulfonylbenzoic acid, 50 ml of dioxan, 3.02 ml of triethylamine and 3 g of isobutyl chloroformate were introduced into a 250 ml balloon flask at ambient temperature.
After the mixture had been stirred for 30 minutes, 3 g of N,N_x0002_diethylethylenediamine were added. The reaction mixture was stirred for 6 hours and the solvents were evaporated under vacuum.
The residue was dissolved in 50 ml of water and the solution was made alkaline with sodium hydroxide. The precipitate formed was filtered, washed and dried in a drying oven at 60°C. 6 g of N-(diethylaminoethyl)-2-methoxy- 5-methylsulfonylbenzamide (melting point: 124°C to 125°C) was produced.
[Brand name]

Tiapride Hydrochloride is JAN.
[Therapeutic Function]

Antiemetic
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

51012-32-9(sigmaaldrich)
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