| Identification | Back Directory | [Name]
4-phenyl-N-(4,4,6-trimethyl-1H-pyrimidin-2-yl)quinazolin-2-amine | [CAS]
511514-03-7 | [Synonyms]
0990CL
185582
4-phenyl-N-(4,4,6-trimethyl-1H-pyrimidin-2-yl)quinazolin-2-amine
2-Quinazolinamine, N-(1,6-dihydro-4,6,6-trimethyl-2-pyrimidinyl)-4-phenyl-
(4-phenyl-quinazolin-2-yl)-(4,6,6-trimethyl-1,6-dihydro-pyrimidin-2-yl)-amine | [Molecular Formula]
C21H21N5 | [MDL Number]
MFCD31714167 | [MOL File]
511514-03-7.mol | [Molecular Weight]
343.42 |
| Chemical Properties | Back Directory | [Boiling point ]
519.5±58.0 °C(Predicted) | [density ]
1.21±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 50 mg/mL (145.59 mM; Need ultrasonic) | [form ]
Solid | [pka]
7.10±0.60(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
0990CL is a specific heterotrimeric Gαi subunit inhibitor by direct interaction with Gαi. 0990CL is able to block α2AR mediated regulation of cAMP[1]. | [storage]
Store at -20°C | [References]
[1] Appleton KM,et al. Development of inhibitors of heterotrimeric Gαi subunits.Bioorg Med Chem. 2014 Jul 1;22(13):3423-34. DOI:10.1016/j.bmc.2014.04.035 |
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| Company Name: |
ChemShuttle, Inc.
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| Telephone: |
0510-83588313-811 18800520310 |
| Website: |
www.jiehuapharma.com/ |
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