| Identification | Back Directory | [Name]
5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide | [CAS]
515866-67-8 | [Synonyms]
WAY-620147
5-bromo-N-(2-morpholinoethyl)nicotinamide
5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide
3-Pyridinecarboxamide, 5-bromo-N-[2-(4-morpholinyl)ethyl]- | [Molecular Formula]
C12H16BrN3O2 | [MDL Number]
MFCD04225865 | [MOL File]
515866-67-8.mol | [Molecular Weight]
314.18 |
| Chemical Properties | Back Directory | [Melting point ]
107-109 °C | [Boiling point ]
465.4±45.0 °C(Predicted) | [density ]
1.426±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
13.70±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
WAY-620147 (compound 6) is an N-(2-morpholinoethyl)nicotinamide derivative that inhibits monoamine oxidase (Monoamine Oxidase). WAY-620147 inhibits MAO-A and MAO-B with IC50s of 26 μM and 55 μM, respectively[1]. | [References]
[1] Shi L, et al. Design of novel nicotinamides as potent and selective monoamine oxidase a inhibitors. Bioorg Med Chem. 2010 Feb 15;18(4):1659-64. DOI:10.1016/j.bmc.2009.12.065 |
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