ChemicalBook--->CAS DataBase List--->521-18-6

521-18-6

521-18-6 Structure

521-18-6 Structure
IdentificationMore
[Name]

Stanolone
[CAS]

521-18-6
[Synonyms]

17BETA-HYDROXY-5ALPHA-ANDROSTAN-3-ONE
17b-hydroxy-5a-androstan-3-one
4,5ALPHA-DIHYDROTESTOSTERONE
4-dihydrotestosterone
5A-ANDROSTAN-17B-OL-3-ONE
5A-DIHYDROTESTOSTERONE
5ALPHA-ANDROSTAN-17BETA-OL-3-ONE
5-ALPHA-ANDROSTANOLONE
5ALPHA-DIHYDROTESTOSTERONE
5ALPHA-DIHYDROTESTOSTOSTERONE
(5S,8R,9S,10S,13S,14S,17S)-17-HYDROXY-10,13-DIMETHYL-HEXADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE
ALLODIHYDROTESTOSTERONE
ANDROSTANOLONE
DHT
DIHYDROTESTOSTERONE
STANOLONE
(5-alpha,17-beta)-17-hydroxyandrostan-3-one
(5alpha,17beta)-17-Hydroxy-androstan-3-one
17beta-Hydroxy-3-androstanone
17-beta-hydroxy-5-alpha-androstan-3-on
[EINECS(EC#)]

208-307-3
[Molecular Formula]

C19H30O2
[MDL Number]

MFCD00003667
[Molecular Weight]

290.44
[MOL File]

521-18-6.mol
Chemical PropertiesBack Directory
[Appearance]

White Crystalline Solid
[Melting point ]

178-183 °C
[alpha ]

27 º
[Boiling point ]

372.52°C (rough estimate)
[density ]

1.0320 (rough estimate)
[refractive index ]

1.4709 (estimate)
[Fp ]

9℃
[storage temp. ]

2-8°C
[solubility ]

Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
[form ]

neat
[pka]

15.08±0.60(Predicted)
[biological source]

synthetic
[Optical Rotation]

[α]20/D +33±1°, c =1% in ethanol
[Water Solubility ]

344.3g/L(temperature not stated)
[Usage]

Anabolic steroid. Controlled substance
[Merck ]

13,8872
[BRN ]

2056371
[Major Application]

forensics and toxicology
pharmaceutical (small molecule)
[InChI]

1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12,14-17,21H,3-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1
[InChIKey]

NVKAWKQGWWIWPM-ABEVXSGRSA-N
[SMILES]

[H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CCC(=O)C2
[CAS DataBase Reference]

521-18-6(CAS DataBase Reference)
[NIST Chemistry Reference]

Stanolone(521-18-6)
[EPA Substance Registry System]

Androstan-3-one, 17-hydroxy-, (5.alpha.,17.beta.)- (521-18-6)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
GHS07,GHS08,GHS09
[Signal word ]

Danger
[Hazard statements ]

H302-H351-H360FD-H410
[Precautionary statements ]

P202-P264-P270-P273-P301+P312-P308+P313
[Hazard Codes ]

Xn
[Risk Statements ]

R61:May cause harm to the unborn child.
R40:Limited evidence of a carcinogenic effect.
[Safety Statements ]

S53:Avoid exposure-obtain special instruction before use .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
[RIDADR ]

UN1230 - class 3 - PG 2 - Methanol, solution
[WGK Germany ]

3
[RTECS ]

BV8052000
[REACH Registrations]

Inactive
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Carc. 2
Repr. 1A
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

4-Dihydrotestosterone(521-18-6).msds
Hazard InformationBack Directory
[Description]

Stanolone is well known as dihydrotestosterone (DHT), which is an endogenous androgen sex steroid and hormone. It is an agonist of the androgen receptor (AR). It plays important physiological role in sexual differentiation, maturation of the penis and scrotum, hair, sebum production and development and maintenance of the prostate gland and seminal vesicles. It is mainly used for the treatment of male hypogonadism, androgen deficiency of severe illness, androgen deficiency of ageing and microphallus in infancy.
[Chemical Properties]

White Crystalline Solid
[Originator]

Neodrol,Pfizer,US,1953
[Uses]

Anabolic steroid. Controlled substance
[Definition]

ChEBI: A 17beta-hydroxy steroid that is testosterone in which the 4-5 double bond has been reduced to a single bond with alpha- configuration at position 5.
[Manufacturing Process]

A solution of 1.0 g of 3,17-androstandione in 50 ml of methanol and containing 1 g of selenium dioxide, was allowed to remain in an ice-chest overnight. The formed 3,3-dimethoxyandrostan-17-one was not separated. 1 g of solid potassium hydroxide and 2.5 g of sodium borohydride in 2.5 ml of water were added and the mixture allowed to react at room temperature for 24 hours. The solution was then poured into a large excess of water, extracted with methylene chloride, the organic layer dried and evaporated to a residue. The residue was dissolved in ether, and a small amount of selenium removed by filtration. The ether was boiled off and the organic material dissolved in 100 ml of boiling acetone. 25 ml of diluted hydrochloric acid were added, the solution boiled for 5 minutes and then allowed to cool. Upon crystallization, 0.85 g of androstan-17β-ol-3-one was obtained, melting point 175°C to 178°C.
[Therapeutic Function]

Androgen
[General Description]

Dihydrotestosterone (Item No. 15874) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including dihydrotestosterone, have been used to enhance physical performance in athletes. Dihydrotestosterone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.
[Side effects]

In rare cases, serious and even fatal cases of liver problems have developed during treatment with stanozolol. Contact your doctor immediately if you experience abdominal pain, light-colored stools, dark-colored urine, unusual fatigue, nausea or vomiting, or yellowing of the skin or eyes. These may be early signs of liver problems.
Serious side effects: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); swelling of the arms or legs (especially ankles); frequent or persistent erections, or breast tenderness or enlargement (male patients); or voice changes (hoarseness, deepening), hair loss, facial hair growth, clitoral enlargement, or menstrual irregularities (female patients).
Common stanozolol side effects may include: new or worsening acne; difficulty sleeping; headache; or changes in sexual desire.
[References]

https://en.wikipedia.org/wiki/Dihydrotestosterone#Medical_use
Swerdloff, R. S., and C. Wang. "Dihydrotestosterone: a rationale for its use as a non-aromatizable androgen replacement therapeutic agent."Baillieres Clin Endocrinol Metab 12.3(1998):501.
Spectrum DetailBack Directory
[Spectrum Detail]

Stanolone(521-18-6)1HNMR
Stanolone(521-18-6)13CNMR
Stanolone(521-18-6)IR1
Stanolone(521-18-6)IR2
Well-known Reagent Company Product InformationBack Directory
[Sigma Aldrich]

521-18-6(sigmaaldrich)
521-18-6 suppliers list
Company Name: Shanghai Beiwanta Biotechnology Co., Ltd.  Gold
Telephone: 021-67187366 19901745723
Website: http://www.bwtlab.com/
Company Name: Shandong Baixinchangda Biotechnology Co., Ltd  Gold
Telephone: 19229895729 19229895729
Website: https://www.Biotechnology.comcom
Company Name: Changsha Tianyang Biotechnology Co., Ltd.  Gold
Telephone: 19558384994 19558384994
Website: www.tianyangshnegwu.com
Company Name: Nanjing Ujijing Biotechnology Co., Ltd.  Gold
Telephone: 17751427757 17751427757
Website:
Company Name: TAIYUAN RHF CO.,LTD.  
Telephone: +86 351 7031519
Website: www.rhfchem.com
Company Name: Energy Chemical  
Telephone: 400-0056266
Website: www.energy-chemical.com
Company Name: Beijing Ouhe Technology Co., Ltd  
Telephone: 13552068683 13522913783
Website: www.ouhetech.cn/
Company Name: Adamas Reagent, Ltd.  
Telephone: 400-6009262 15618770481
Website: www.tansoole.com
Company Name: China DongFan Chemical Co.,LTD  
Telephone: 86-0571-85151182
Website: www.chemicalbook.com/ShowSupplierProductsList14819/0_EN.htm
Company Name: Shandong Xiya Chemical Co., Ltd  
Telephone: 13355009207 13355009207
Website: http://www.xiyashiji.com
Company Name: Syntechem Co.,Ltd  
Telephone:
Website: www.syntechem.com
Company Name: Sichuan Kulinan Technology Co., Ltd  
Telephone: 400-1166-196 18981987031
Website: http://www.hx-r.com/
Company Name: Sphinx Scientific Laboratory (Tianjin) Co., Ltd.  
Telephone: 022-66211289-843 13672102692
Website: www.sphinxpharm.com
Company Name: Spectrum Chemical Manufacturing Corp.  
Telephone: 021-021-021-67601398-809-809-809 15221380277
Website: www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us
Company Name: BioBioPha Co., Ltd.  
Telephone: 0871-65217109
Website: http://www.biobiopha.com
Company Name: T&W GROUP  
Telephone: 021-61551611 13296011611
Website: www.trustwe.com/
Company Name: NCE Biomedical Co.,Ltd.  
Telephone: 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Website: www.chemicalbook.com/ShowSupplierProductsList15748/0_EN.htm
Company Name: UHN Shanghai Research & Development Co., Ltd.  
Telephone: 021-58958002 18930822973
Website: www.uhnshanghai.com
Tags:521-18-6 Related Product Information
153-00-4 1914-99-4 1257527-54-0 521-11-9 2088-71-3 1424-00-6 58-22-0 434-22-0 521-18-6