| Identification | Back Directory | [Name]
tetranor-PGAM | [CAS]
52510-53-9 | [Synonyms]
tetranor-PGAM
tetranor-PGAM Exclusive
HYPIFMOQVFWSBF-WCQYABFASA-N
tetranor-prostaglandin A metabolite
2-Cyclopentene-1-octanoic acid, 5-(2-carboxyethyl)-ε,4-dioxo-, (1S,5R)- | [Molecular Formula]
C16H22O6 | [MOL File]
52510-53-9.mol | [Molecular Weight]
310.35 |
| Hazard Information | Back Directory | [Description]
Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis. Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a surrogate for tetranor-PGEM levels in urine. | [Definition]
ChEBI: Tetranor-PGAM is an oxo carboxylic acid. |
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