| Chemical Properties | Back Directory | [Boiling point ]
902.3±75.0 °C(Predicted) | [density ]
2.01±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [pka]
2.11±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
SAHO2 is the sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride (SAM) and serves as a substrate for radical SAM enzymes[1]. | [Biological Activity]
SAHO2 is a sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and is a substrate for radical SAM enzymes.1 It is reductively cleaved to 5'-deoxyadenosine and 5'-thioadenosine sulfinic acid by the radical SAM enzymes NosL or NosN. | [References]
1.Mandalapu, D., Ji, X., and Zhang, Q.Reductive cleavage of sulfoxide and sulfone by two radical S-adenosyl-L-methionine enzymesBiochemistry58(1)36-39(2019)
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