| Identification | More | [Name]
5-Chloropyrimidin-2-amine | [CAS]
5428-89-7 | [Synonyms]
2-AMINO-5-CHLOROPYRIMIDINE
5-CHLORO-2-PYRIMIDINAMINE
TIMTEC-BB SBB005486
2-amino-5-chloro-pyrimidin
2-Pyrimidinamine, 5-chloro-
5-chloro-2-pyrimidinamin
Pyrimidine, 2-amino-5-chloro-
5-chloropyrimidin-2-amine
2-Pyrimidinamine, 5-chloro-(9CI)
2-Amino-5-chloropyridine
5-chloro-2-pyrimidinylamine | [EINECS(EC#)]
226-581-2 | [Molecular Formula]
C4H4ClN3 | [MDL Number]
MFCD00014604 | [Molecular Weight]
129.55 | [MOL File]
5428-89-7.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R41:Risk of serious damage to eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
UV6329500
| [Hazard Note ]
Irritant | [TSCA ]
Yes | [HazardClass ]
6.1 | [PackingGroup ]
Ⅲ | [HS Code ]
29335990 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral
Eye Dam. 1 |
| Hazard Information | Back Directory | [Uses]
5-Chloropyrimidin-2-amine is an useful reagent of research interest in the preparation of JAK2 inhibitors for the treatment of myeloproliferative disorders and SIRT2 inhibitors for the treatment of Huntington''s disease. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 64, p. 567, 1942 DOI: 10.1021/ja01255a030 |
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