| Identification | More | [Name]
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE | [CAS]
55-43-6 | [Synonyms]
DIBENAMINE HYDROCHLORIDE
N-(2-CHLOROETHYL)DIBENZYLAMINE HCL
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
N,N'-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE
N,N-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE
N,N-DIBENZYLAMINOETHYLCHLORIDE HYDROCHLORIDE
N,N-DIBENZYL-BETA-CHLOROETHYLAMINE HYDROCHLORIDE
dibenzylchlorethylaminehydrochloride
n-(2-chloroethyl)-dibenzylaminhydrochloride
n-(2-chloroethyl)-n-(phenylmethyl)-benzenemethanaminhydrochloride
dibenzyl(2-chloroethyl)ammonium chloride
n,n-dibenzyl-2-chloroethylamineHCl
DIBENZYLAMINE,N-(2-CHLOROETHYL)-,HYDROCHLORIDE
N-(2-Chloroethyl)-N-(phenylmethyl)benzmetanamine chlorohydrate
Sympatholytin hydrochloride | [EINECS(EC#)]
200-234-5 | [Molecular Formula]
C16H19Cl2N | [MDL Number]
MFCD00012518 | [Molecular Weight]
296.23 | [MOL File]
55-43-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
190-193 °C(lit.) | [Boiling point ]
449.72°C (rough estimate) | [density ]
1.1507 (rough estimate) | [refractive index ]
1.6300 (estimate) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
almost transparency in Methanol | [form ]
Crystalline Powder | [color ]
White to off-white | [Merck ]
2138 | [InChI]
1S/C16H18ClN.ClH/c17-11-12-18(13-15-7-3-1-4-8-15)14-16-9-5-2-6-10-16;/h1-10H,11-14H2;1H | [InChIKey]
LZXCEBPGNFLHEQ-UHFFFAOYSA-N | [SMILES]
Cl.ClCCN(Cc1ccccc1)Cc2ccccc2 | [CAS DataBase Reference]
55-43-6(CAS DataBase Reference) | [EPA Substance Registry System]
N-(2-Chloroethyl)dibenzylamine hydrochloride (55-43-6) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [RTECS ]
HQ6825000
| [HazardClass ]
IRRITANT | [HS Code ]
29214900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 | [Toxicity]
LD50 s.c. in mice: 800 mg/kg (Nickerson, Nomaguchi) |
| Hazard Information | Back Directory | [Uses]
Sympatholytin was used as 5-Hydroxytryptamine antagonists in this study.Sympatholytin preferentially blocked postsynaptic alpha receptors. | [General Description]
N-(2-Chloroethyl)dibenzylamine hydrochloride is also referred as dibenamine. Mechanism of protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with [N-(2-chloroethyl) dibenzylamine] hydrochloride has been investigated. It is a powerful adrenergic blocking agent, is known to modify the pharmacological effects of epinephrine. | [in vivo]
Dibenamine hydrochloride (subcutaneous?injection; 25 mg/kg; 48 and 24 hr before the administration of CCl4) decreases the CHCl3, levels at 2 and 6 hr by 30-50 percent, but did not appreciably affect the half-life of CHCl3, in the liver.Pretreatment with Dibenamine apparently slows the conversion of Ccl4 to CHCL3[1]. |
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