ChemicalBook--->CAS DataBase List--->554438-52-7

554438-52-7

554438-52-7 Structure

554438-52-7 Structure
IdentificationBack Directory
[Name]

LASV inhibitor 3.3
[CAS]

554438-52-7
[Synonyms]

LASV-IN-3.3
LASV inhibitor 3.3
Tricyclo[3.3.1.13,7]decane-1-carboxamide, N-[2-[4-(diphenylmethyl)-1-piperazinyl]-2-oxoethyl]-
[Molecular Formula]

C30H37N3O2
[MOL File]

554438-52-7.mol
[Molecular Weight]

471.63
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

LASV-IN-3.3 is a specific inhibitor of Lassa fever virus (LASV) which targets lysosome-associated membrane protein 1 (LAMP1), which is a host factor that binds to the LASV glycoprotein (GP) during infection.
[Uses]

LASV inhibitor 3.3 is a Lassa fever virus (LASV) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV inhibitor 3.3 can be used for LASV infection research[1].
[References]

[1] Wang MK, et al. Critical role for cholesterol in Lassa fever virus entry identified by a novel small molecule inhibitor targeting the viral receptor LAMP1. PLoS Pathog. 2018 Sep 28;14(9):e1007322.
Spectrum DetailBack Directory
[Spectrum Detail]

LASV inhibitor 3.3(554438-52-7)1HNMR
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