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55779-18-5

55779-18-5 Structure

55779-18-5 Structure
IdentificationMore
[Name]

Arprinocide
[CAS]

55779-18-5
[Synonyms]

9-[(2-CHLORO-6-FLUOROPHENYL)METHYL]-9H-PURIN-6-AMINE
ARPRINOCID
arprinocide
9-[(2-Chloro-6-fluorophenyl)methyl]-9H-purine-6-amine
Arpronocid
9-[(2-Chloro-6-fluorophenyl)methyl]purin-6-amine
6-Amino-9-(2-chloro-6-fluorobenzyl)purine
9H-Purin-6-amine, 9-[(2-chloro-6-fluorophenyl)methyl]-
Arpocox
MK-302
[EINECS(EC#)]

259-817-8
[Molecular Formula]

C12H9ClFN5
[MDL Number]

MFCD00867210
[Molecular Weight]

277.68
[MOL File]

55779-18-5.mol
Chemical PropertiesBack Directory
[Melting point ]

245-246°
[Boiling point ]

504.6±60.0 °C(Predicted)
[density ]

1.568 g/cm3
[storage temp. ]

Keep in dark place,Inert atmosphere,2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

3.91±0.10(Predicted)
[color ]

Pale Yellow to Pale Beige
[λmax]

260nm(NaOH aq.)(lit.)
[CAS DataBase Reference]

55779-18-5(CAS DataBase Reference)
Safety DataBack Directory
[HS Code ]

2933.59.3600
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

9-[(2-Chloro-6-fluorophenyl)methyl]purin-6-amine(55779-18-5).msds
Hazard InformationBack Directory
[Chemical Properties]

Pale Yellow Solid
[Originator]

Arprinocid,NANJING PHARMA
[Uses]

Arprinocide can be used as a Coccidiostat used in veterinary medicine.
[Definition]

ChEBI: Arprinocid is a member of 6-aminopurines.
[Manufacturing Process]

To a solution of potassium t-butoxide in absolute ethanol slowly adding dry adenine. This mixture was stirred for about 2 h, and then 2-chloro-6- fluorobenzyl chloride was added over a period of about 4 h. The resulting mixture was heated to reflux with stirring and allowed to react for about 42 h, after which it was cooled to about 10°C. The crude product thus formed was isolated by filtration and then washed with ice cold ethanol and ice cold water to yield a 6-amino-9-(2-chloro-6-fluorobenzyl)purine.
[Brand name]

Arpocox (Merck).
[Therapeutic Function]

Coccidiostatic
[Synthesis Reference(s)]

The Journal of Organic Chemistry, 43, p. 960, 1978 DOI: 10.1021/jo00399a034
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