| Identification | Back Directory | [Name]
1,2-diarachidonoyl-glycero-3-phosphoethanolamine | [CAS]
5634-86-6 | [Synonyms]
1,2-Diarachidonoyl-sn-glycero-3-PE
1,2-diarachidonoyl-glycero-3-phosphoethanolamine
[(2R)-3-[2-aminoethoxy(hydroxy)phosphoryl]oxy-2-[(5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoyl]oxypropyl] (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate
5,8,11,14-Eicosatetraenoic acid, 2-ethyl-2-(hydroxymethyl)-, 1,1'-[(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester, (5Z,5'Z,8Z,8'Z,11Z,11'Z,14Z,14'Z)- | [Molecular Formula]
C45H74NO8P | [MDL Number]
MFCD00674343 | [MOL File]
5634-86-6.mol | [Molecular Weight]
788.06 |
| Chemical Properties | Back Directory | [Boiling point ]
792.0±70.0 °C(Predicted) | [density ]
1.029±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Ethanol: 10 mg/ml | [form ]
liquid | [pka]
1.17±0.50(Predicted) | [InChIKey]
JTERLNYVBOZRHI-RIIGGKATSA-N | [SMILES]
[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O |
| Hazard Information | Back Directory | [Uses]
1,2-Diarachidonoyl-sn-glycero-3-phosphoethanolamine is used in the preparation of amino lipide compounds and their nanoparticle compositions for intracellular delivery of therapeutic agents. | [Biological Activity]
Phosphatidylethanolamine (PE) is implicated in a numerous function like membrane fusioncell cycleautophagyapoptosisand cognitive function. 20:4 phosphatidylethanolamine (PE)/ DAPE induces cell death in malignant pleural mesothelioma (MPM) cells. DAPE enhances protein phosphatase 2A (PP2A) and protein tyrosine phosphatase 1B (PTB1B) activity. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Creative Enzymes
|
| Tel: |
1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
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