| Identification | More | [Name]
(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE | [CAS]
56881-90-4 | [Synonyms]
2(3H)-FURANONE, DIHYDRO-3-HYDROXY-, (R)
(R)-2-HYDROXYBUTYROLACTONE
(R)-2-HYDROXY-GAMMA-BUTYROLACTONE
(R)-(+)-3-HYDROXYTETRAHYDROFURAN-2-ONE
(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE
RARECHEM AK HZ 0027
(R)-(+)-DIHYDRO-3-HYDROXY-2(3H)-FURANONE
(R)-(+)-α-Hydroxy-γ-butyrolactone
(r)-4,5-dihydro-3-hydroxy-2(3h)-furanone
(R)-(+)-ALPHA-HYDROXY-GAMMA-BUTYROLACTONE 98+% | [Molecular Formula]
C4H6O3 | [MDL Number]
MFCD00211246 | [Molecular Weight]
102.09 | [MOL File]
56881-90-4.mol |
| Chemical Properties | Back Directory | [alpha ]
+66°(23℃, c=1.15, CHCl3) | [Boiling point ]
133 °C/10 mmHg (lit.) | [density ]
1.309 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.467(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C | [form ]
clear liquid | [pka]
13.07±0.20(Predicted) | [color ]
Colorless to Light yellow | [Specific Gravity]
1.32 | [Optical Rotation]
[α]23/D +66°, c = 1.15 in chloroform | [BRN ]
80588 | [InChI]
1S/C4H6O3/c5-3-1-2-7-4(3)6/h3,5H,1-2H2/t3-/m1/s1 | [InChIKey]
FWIBCWKHNZBDLS-GSVOUGTGSA-N | [SMILES]
O[C@@H]1CCOC1=O | [CAS DataBase Reference]
56881-90-4(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Uses]
(R)-(+)-α-Hydroxy-γ-butyrolactone can be used as a starting material to synthesize:
- δ-Azaproline by reacting with benzyloxycarbonyl aminophthalimide via Mitsunobu reactions.
- Homochiral (R)-2,4-dihydroxybutyramide seco-pseudonucleoside reagents.
- Botryolide B via esterification and ring-closing metathesis reaction.
- Pregnane derivatives containing γ-butyrolactones as potential glucocorticoid agonists.
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