| Identification | Back Directory | [Name]
2-broMo-5-ethynylpyridine | [CAS]
569672-28-2 | [Synonyms]
2-broMo-5-ethynylpyridine
Pyridine, 2-bromo-5-ethynyl- | [Molecular Formula]
C7H4BrN | [MDL Number]
MFCD13189724 | [MOL File]
569672-28-2.mol | [Molecular Weight]
182.02 |
| Chemical Properties | Back Directory | [Melting point ]
83℃ | [Boiling point ]
231.0±25.0 °C(Predicted) | [density ]
1.60±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [pka]
-0.73±0.10(Predicted) | [InChI]
InChI=1S/C7H4BrN/c1-2-6-3-4-7(8)9-5-6/h1,3-5H | [InChIKey]
WRORYOXBXUUDJL-UHFFFAOYSA-N | [SMILES]
C1(Br)=NC=C(C#C)C=C1 |
| Hazard Information | Back Directory | [Uses]
2-Bromo-5-ethynylpyridine is used in the synthesis of macrocycle of terpyridine units. | [Preparation]
The iodobromopyridine (2-Bromo-5-iodopyridine), the starting material, was coupled with TMS-acetylene under Sonogashira conditions. One-pot deprotection and recrystallization could yield the bromo,ethynyl-functionalized pyridine (2-Bromo-5-ethynylpyridine)[1].
| [Reactions]
2-Bromo-5-ethynylpyridine is a useful organic compound that could be used to synthesize 2-Bromo-5-[(3-iodophenyl)ethynyl]pyridine, 2-bromo-5-({4-[(tert-butyldimethylsilyl)oxy]phenyl}ethynyl)pyridine, and so on. |
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