| Identification | More | [Name]
2-Bromo-5-methylpyridine | [CAS]
3510-66-5 | [Synonyms]
2-BROMO-5-METHYLPYRIDINE
2-BROMO-5-PICOLINE
6-BROMO-3-PICOLINE
2-BROMO-5-METHYLPYRIDINE 98%
2-Bromo5MythylPyridine
2-BROMO-5-METHYLPYRIDINE (2-BROMO-5-PICOLINE)
2-Bromo-5-methylpyridine, 98+%
6-Bromo-β-picoline | [EINECS(EC#)]
609-062-9 | [Molecular Formula]
C6H6BrN | [MDL Number]
MFCD00209553 | [Molecular Weight]
172.02 | [MOL File]
3510-66-5.mol |
| Chemical Properties | Back Directory | [Appearance]
Light Brown Solid | [Melting point ]
41-43 °C (lit.) | [Boiling point ]
95-96 °C/12.5 mmHg (lit.) | [density ]
1.4964 (rough estimate) | [refractive index ]
1.5680 (estimate) | [Fp ]
218 °F
| [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Dimethyl Sulfoxide, Methanol, | [form ]
Low Melting Crystalline Solid or Crystals | [pka]
1.08±0.10(Predicted) | [color ]
White to light yellow or pale brown | [Detection Methods]
GC,NMR | [BRN ]
107323 | [InChI]
InChI=1S/C6H6BrN/c1-5-2-3-6(7)8-4-5/h2-4H,1H3 | [InChIKey]
YWNJQQNBJQUKME-UHFFFAOYSA-N | [SMILES]
C1(Br)=NC=C(C)C=C1 | [CAS DataBase Reference]
3510-66-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29333990 |
| Questions And Answer | Back Directory | [Structure]
The crystal structure of 2-Bromo-5-methylpyridine was reported. The planar molecule lies on a crystallographic plane of symmetry, with a half molecule in the asymmetric unit. The only intermolecular interactions observed are weak tip-to-tail C3—H3···N1 interactions that form infinite chains along[100]. Similar C—H···N interactions have been observed in other5-substituted 2-bromopyridines, though not in the closely related 2,6-dibromo-3,5-dimethylpyridine.There are no other significant intermolecular interactions present[1].
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| Hazard Information | Back Directory | [Chemical Properties]
2-Bromo-5-methylpyridine is Light Brown Solid
| [Uses]
2-Bromo-5-methylpyridine is used for preparation of [[(triazolylmethyl)pyridyl]phenyl]tetrazoles and related compounds as cardiovascular agents.
| [References]
[1] Mrittika Roy, David R. Manke, J. Golen. “2-Bromo-5-methyl-pyridine.” IUCrData 26 10 (2016). |
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